PaHa_c224g00010

Functional evidence

eggNOG

Preferred name: RBX1 | Seed ortholog: 337451.A0A443PMH2 | COG: S | eggNOG OG: zf-rbx1@131567|Gg-12, zf-rbx1@2759|IE-13!

Gene Ontology

GO:0000045 autophagosome assembly; GO:0000082 G1/S transition of mitotic cell cycle; GO:0000086 G2/M transition of mitotic cell cycle; GO:0000109 nucleotide-excision repair complex; GO:0000122 negative regulation of transcription by RNA polymerase II; GO:0000151 ubiquitin ligase complex; GO:0000165 MAPK cascade; GO:0000209 protein polyubiquitination; GO:0000409 regulation of transcription by galactose; GO:0000423 mitophagy; GO:0001837 epithelial to mesenchymal transition; GO:0003222 ventricular trabecula myocardium morphogenesis; GO:0004842 ubiquitin-protein transferase activity; GO:0005507 copper ion binding; GO:0005515 protein binding; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0005680 anaphase-promoting complex; GO:0005721 pericentric heterochromatin; GO:0005737 cytoplasm; GO:0005794 Golgi apparatus; GO:0005813 centrosome; GO:0005829 cytosol; GO:0006260 DNA replication; GO:0006275 regulation of DNA replication; GO:0006283 transcription-coupled nucleotide-excision repair; GO:0006289 nucleotide-excision repair; GO:0006334 nucleosome assembly; GO:0006355 regulation of DNA-templated transcription; GO:0006366 transcription by RNA polymerase II; GO:0006368 transcription elongation by RNA polymerase II; GO:0006508 proteolysis; GO:0006511 ubiquitin-dependent protein catabolic process; GO:0006513 protein monoubiquitination; GO:0006879 intracellular iron ion homeostasis; GO:0006915 apoptotic process; GO:0006974 DNA damage response; GO:0006979 response to oxidative stress; GO:0007040 lysosome organization; GO:0007283 spermatogenesis; GO:0007346 regulation of mitotic cell cycle; GO:0008053 mitochondrial fusion; GO:0008150 biological_process; GO:0008190 eukaryotic initiation factor 4E binding; GO:0008270 zinc ion binding; GO:0008283 cell population proliferation; GO:0008286 insulin receptor signaling pathway; GO:0008595 anterior/posterior axis specification, embryo; GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress; GO:0008637 apoptotic mitochondrial changes; GO:0009733 response to auxin; GO:0009734 auxin-activated signaling pathway; GO:0009753 response to jasmonic acid; GO:0009867 jasmonic acid mediated signaling pathway; GO:0010498 proteasomal protein catabolic process; GO:0010506 regulation of autophagy; GO:0010507 negative regulation of autophagy; GO:0010508 positive regulation of autophagy; GO:0010564 regulation of cell cycle process; GO:0010623 programmed cell death involved in cell development; GO:0010824 regulation of centrosome duplication; GO:0010828 positive regulation of D-glucose transmembrane transport; GO:0014033 neural crest cell differentiation; GO:0016032 viral process; GO:0016485 protein processing; GO:0016567 protein ubiquitination; GO:0019005 SCF ubiquitin ligase complex; GO:0019788 NEDD8 transferase activity; GO:0019915 lipid storage; GO:0020011 apicoplast; GO:0021799 cerebral cortex radially oriented cell migration; GO:0021942 radial glia guided migration of Purkinje cell; GO:0030163 protein catabolic process; GO:0030174 regulation of DNA-templated DNA replication initiation; GO:0030238 male sex determination; GO:0030330 DNA damage response, signal transduction by p53 class mediator; GO:0030335 positive regulation of cell migration; GO:0030466 silent mating-type cassette heterochromatin formation; GO:0030510 regulation of BMP signaling pathway; GO:0030674 protein-macromolecule adaptor activity; GO:0030891 VCB complex; GO:0030968 endoplasmic reticulum unfolded protein response; GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0031297 replication fork processing; GO:0031461 cullin-RING ubiquitin ligase complex; GO:0031462 Cul2-RING ubiquitin ligase complex; GO:0031463 Cul3-RING ubiquitin ligase complex; GO:0031464 Cul4A-RING E3 ubiquitin ligase complex; GO:0031465 Cul4B-RING E3 ubiquitin ligase complex; GO:0031466 Cul5-RING ubiquitin ligase complex; GO:0031467 Cul7-RING ubiquitin ligase complex; GO:0031507 heterochromatin formation; GO:0031508 pericentric heterochromatin formation; GO:0031509 subtelomeric heterochromatin formation; GO:0031573 mitotic intra-S DNA damage checkpoint signaling; GO:0031625 ubiquitin protein ligase binding; GO:0031669 cellular response to nutrient levels; GO:0032006 regulation of TOR signaling; GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0032480 negative regulation of type I interferon production; GO:0032481 positive regulation of type I interferon production; GO:0032814 regulation of natural killer cell activation; GO:0032869 cellular response to insulin stimulus; GO:0034198 cellular response to amino acid starvation; GO:0034450 ubiquitin-ubiquitin ligase activity; GO:0034599 cellular response to oxidative stress; GO:0034644 cellular response to UV; GO:0035279 miRNA-mediated gene silencing by mRNA destabilization; GO:0035361 Cul8-RING ubiquitin ligase complex; GO:0038026 reelin-mediated signaling pathway; GO:0038066 p38MAPK cascade; GO:0038162 erythropoietin-mediated signaling pathway; GO:0038202 TORC1 signaling; GO:0040029 epigenetic regulation of gene expression; GO:0042110 T cell activation; GO:0042127 regulation of cell population proliferation; GO:0042752 regulation of circadian rhythm; GO:0042770 signal transduction in response to DNA damage; GO:0042981 regulation of apoptotic process; GO:0043066 negative regulation of apoptotic process; GO:0043123 positive regulation of canonical NF-kappaB signal transduction; GO:0043124 negative regulation of canonical NF-kappaB signal transduction; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043224 nuclear SCF ubiquitin ligase complex; GO:0043494 CLRC complex; GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator; GO:0043687 post-translational protein modification; GO:0044314 protein K27-linked ubiquitination; GO:0044877 protein-containing complex binding; GO:0045087 innate immune response; GO:0045116 protein neddylation; GO:0045724 positive regulation of cilium assembly; GO:0045727 positive regulation of translation; GO:0045732 positive regulation of protein catabolic process; GO:0045879 negative regulation of smoothened signaling pathway; GO:0045944 positive regulation of transcription by RNA polymerase II; GO:0045995 regulation of embryonic development; GO:0046314 phosphocreatine biosynthetic process; GO:0046627 negative regulation of insulin receptor signaling pathway; GO:0050727 regulation of inflammatory response; GO:0051298 centrosome duplication; GO:0051607 defense response to virus; GO:0051726 regulation of cell cycle; GO:0051759 sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation; GO:0051775 response to redox state; GO:0051894 positive regulation of focal adhesion assembly; GO:0051895 negative regulation of focal adhesion assembly; GO:0060090 molecular adaptor activity; GO:0060173 limb development; GO:0060271 cilium assembly; GO:0060337 type I interferon-mediated signaling pathway; GO:0060396 growth hormone receptor signaling pathway; GO:0060397 growth hormone receptor signaling pathway via JAK-STAT; GO:0060400 negative regulation of growth hormone receptor signaling pathway; GO:0060964 regulation of miRNA-mediated gene silencing; GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding; GO:0061630 ubiquitin protein ligase activity; GO:0061663 NEDD8 ligase activity; GO:0062197 cellular response to chemical stress; GO:0070534 protein K63-linked ubiquitination; GO:0070936 protein K48-linked ubiquitination; GO:0070979 protein K11-linked ubiquitination; GO:0071230 cellular response to amino acid stimulus; GO:0071406 cellular response to methylmercury; GO:0080008 Cul4-RING E3 ubiquitin ligase complex; GO:0080135 regulation of cellular response to stress; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0090734 site of DNA damage; GO:0097510 base-excision repair, AP site formation via deaminated base removal; GO:0097602 cullin family protein binding; GO:0120184 negative regulation of focal adhesion disassembly; GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway; GO:0140727 siRNA-mediated pericentric heterochromatin formation; GO:0140851 histone H3K14 ubiquitin ligase activity; GO:0140896 cGAS/STING signaling pathway; GO:0160240 RNA polymerase II transcription initiation surveillance; GO:0160276 negative regulation of beige fat cell differentiation; GO:1900076 regulation of cellular response to insulin stimulus; GO:1901524 regulation of mitophagy; GO:1901525 negative regulation of mitophagy; GO:1901797 negative regulation of signal transduction by p53 class mediator; GO:1901987 regulation of cell cycle phase transition; GO:1902104 positive regulation of metaphase/anaphase transition of meiotic cell cycle; GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; GO:1902412 regulation of mitotic cytokinesis; GO:1902499 positive regulation of protein autoubiquitination; GO:1902883 negative regulation of response to oxidative stress; GO:1904037 positive regulation of epithelial cell apoptotic process; GO:1904178 negative regulation of adipose tissue development; GO:1904262 negative regulation of TORC1 signaling; GO:1904263 positive regulation of TORC1 signaling; GO:1904415 regulation of xenophagy; GO:1904801 positive regulation of neuron remodeling; GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process; GO:2000001 regulation of DNA damage checkpoint; GO:2000036 regulation of stem cell population maintenance; GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process; GO:2000104 negative regulation of DNA-templated DNA replication; GO:2001222 regulation of neuron migration

KEGG

EC: ec:2.3.2.32 | KO: K03358, K03868, K10611 | Pathway: 03420, 04066, 04110, 04111, 04114, 04120, 04141, 04310, 04341, 04350, 04710, 05131, 05170, 05200, 05211 | BRITE: 00001, 01000, 03036, 03400, 04121