Pa02g0799

Functional evidence

eggNOG

Preferred name: BnaC08g14190D | Seed ortholog: 337451.A0A3S4N3W8 | COG: S | eggNOG OG: Ank_2@131567|B-2, Ank_2@2759|H-4!, Ank_2@3398|Hv-10, Ank_4@131567|GW-15, Ank_4@1437183|DFt-27, PGG@131567|A-1*, PGG@3193|Aa-7, PGG@33090|a-5, PGG@3398|JG-12

Gene Ontology

GO:0000122 negative regulation of transcription by RNA polymerase II; GO:0000165 MAPK cascade; GO:0000724 double-strand break repair via homologous recombination; GO:0001554 luteolysis; GO:0001568 blood vessel development; GO:0001701 in utero embryonic development; GO:0001708 cell fate specification; GO:0001709 cell fate determination; GO:0001745 compound eye morphogenesis; GO:0001756 somitogenesis; GO:0001822 kidney development; GO:0001837 epithelial to mesenchymal transition; GO:0001838 embryonic epithelial tube formation; GO:0001840 neural plate development; GO:0001889 liver development; GO:0001890 placenta development; GO:0001894 tissue homeostasis; GO:0001944 vasculature development; GO:0001946 lymphangiogenesis; GO:0001947 heart looping; GO:0002011 morphogenesis of an epithelial sheet; GO:0002040 sprouting angiogenesis; GO:0002051 osteoblast fate commitment; GO:0002052 positive regulation of neuroblast proliferation; GO:0002091 negative regulation of receptor internalization; GO:0002093 auditory receptor cell morphogenesis; GO:0002213 defense response to insect; GO:0002244 hematopoietic progenitor cell differentiation; GO:0002315 marginal zone B cell differentiation; GO:0002437 inflammatory response to antigenic stimulus; GO:0003151 outflow tract morphogenesis; GO:0003157 endocardium development; GO:0003160 endocardium morphogenesis; GO:0003162 atrioventricular node development; GO:0003169 coronary vein morphogenesis; GO:0003180 aortic valve morphogenesis; GO:0003181 atrioventricular valve morphogenesis; GO:0003182 coronary sinus valve morphogenesis; GO:0003184 pulmonary valve morphogenesis; GO:0003192 mitral valve formation; GO:0003197 endocardial cushion development; GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation; GO:0003203 endocardial cushion morphogenesis; GO:0003207 cardiac chamber formation; GO:0003208 cardiac ventricle morphogenesis; GO:0003209 cardiac atrium morphogenesis; GO:0003213 cardiac right atrium morphogenesis; GO:0003214 cardiac left ventricle morphogenesis; GO:0003219 cardiac right ventricle formation; GO:0003222 ventricular trabecula myocardium morphogenesis; GO:0003241 growth involved in heart morphogenesis; GO:0003264 regulation of cardioblast proliferation; GO:0003273 cell migration involved in endocardial cushion formation; GO:0003332 negative regulation of extracellular matrix constituent secretion; GO:0003344 pericardium morphogenesis; GO:0003674 molecular_function; GO:0005634 nucleus; GO:0005737 cytoplasm; GO:0006110 regulation of glycolytic process; GO:0006281 DNA repair; GO:0006282 regulation of DNA repair; GO:0006338 chromatin remodeling; GO:0006355 regulation of DNA-templated transcription; GO:0006357 regulation of transcription by RNA polymerase II; GO:0006606 protein import into nucleus; GO:0006915 apoptotic process; GO:0006929 substrate-dependent cell migration; GO:0006955 immune response; GO:0006959 humoral immune response; GO:0006974 DNA damage response; GO:0007015 actin filament organization; GO:0007094 mitotic spindle assembly checkpoint signaling; GO:0007140 male meiotic nuclear division; GO:0007165 signal transduction; GO:0007219 Notch signaling pathway; GO:0007221 positive regulation of transcription of Notch receptor target; GO:0007254 JNK cascade; GO:0007283 spermatogenesis; GO:0007293 germarium-derived egg chamber formation; GO:0007297 follicle cell of egg chamber migration; GO:0007298 border follicle cell migration; GO:0007306 egg chorion assembly; GO:0007346 regulation of mitotic cell cycle; GO:0007368 determination of left/right symmetry; GO:0007386 compartment pattern specification; GO:0007391 dorsal closure; GO:0007394 dorsal closure, elongation of leading edge cells; GO:0007399 nervous system development; GO:0007400 neuroblast fate determination; GO:0007403 glial cell fate determination; GO:0007405 neuroblast proliferation; GO:0007409 axonogenesis; GO:0007411 axon guidance; GO:0007416 synapse assembly; GO:0007420 brain development; GO:0007422 peripheral nervous system development; GO:0007423 sensory organ development; GO:0007440 foregut morphogenesis; GO:0007455 eye-antennal disc morphogenesis; GO:0007474 imaginal disc-derived wing vein specification; GO:0007476 imaginal disc-derived wing morphogenesis; GO:0007478 leg disc morphogenesis; GO:0007480 imaginal disc-derived leg morphogenesis; GO:0007492 endoderm development; GO:0007498 mesoderm development; GO:0007507 heart development; GO:0007521 muscle cell fate determination; GO:0007605 sensory perception of sound; GO:0007611 learning or memory; GO:0007612 learning; GO:0007613 memory; GO:0007616 long-term memory; GO:0007622 rhythmic behavior; GO:0007626 locomotory behavior; GO:0007632 visual behavior; GO:0008045 motor neuron axon guidance; GO:0008150 biological_process; GO:0008284 positive regulation of cell population proliferation; GO:0008285 negative regulation of cell population proliferation; GO:0008306 associative learning; GO:0008340 determination of adult lifespan; GO:0008347 glial cell migration; GO:0008356 asymmetric cell division; GO:0008407 chaeta morphogenesis; GO:0008544 epidermis development; GO:0008587 imaginal disc-derived wing margin morphogenesis; GO:0008593 regulation of Notch signaling pathway; GO:0008608 attachment of spindle microtubules to kinetochore; GO:0009507 chloroplast; GO:0009608 response to symbiont; GO:0009887 animal organ morphogenesis; GO:0009912 auditory receptor cell fate commitment; GO:0009950 dorsal/ventral axis specification; GO:0009952 anterior/posterior pattern specification; GO:0010001 glial cell differentiation; GO:0010458 exit from mitosis; GO:0010467 gene expression; GO:0010468 regulation of gene expression; GO:0010614 negative regulation of cardiac muscle hypertrophy; GO:0010628 positive regulation of gene expression; GO:0010629 negative regulation of gene expression; GO:0010667 negative regulation of cardiac muscle cell apoptotic process; GO:0010718 positive regulation of epithelial to mesenchymal transition; GO:0010812 negative regulation of cell-substrate adhesion; GO:0010832 negative regulation of myotube differentiation; GO:0010838 positive regulation of keratinocyte proliferation; GO:0014003 oligodendrocyte development; GO:0014009 glial cell proliferation; GO:0014018 neuroblast fate specification; GO:0014019 neuroblast development; GO:0014031 mesenchymal cell development; GO:0014807 regulation of somitogenesis; GO:0016197 endosomal transport; GO:0016318 ommatidial rotation; GO:0016322 neuron remodeling; GO:0016330 second mitotic wave involved in compound eye morphogenesis; GO:0016348 imaginal disc-derived leg joint morphogenesis; GO:0016360 sensory organ precursor cell fate determination; GO:0016567 protein ubiquitination; GO:0021514 ventral spinal cord interneuron differentiation; GO:0021515 cell differentiation in spinal cord; GO:0021523 somatic motor neuron differentiation; GO:0021531 spinal cord radial glial cell differentiation; GO:0021654 rhombomere boundary formation; GO:0021773 striatal medium spiny neuron differentiation; GO:0021915 neural tube development; GO:0021986 habenula development; GO:0022416 chaeta development; GO:0030036 actin cytoskeleton organization; GO:0030097 hemopoiesis; GO:0030154 cell differentiation; GO:0030163 protein catabolic process; GO:0030182 neuron differentiation; GO:0030216 keratinocyte differentiation; GO:0030279 negative regulation of ossification; GO:0030324 lung development; GO:0030326 embryonic limb morphogenesis; GO:0030334 regulation of cell migration; GO:0030335 positive regulation of cell migration; GO:0030421 defecation; GO:0030513 positive regulation of BMP signaling pathway; GO:0030514 negative regulation of BMP signaling pathway; GO:0030534 adult behavior; GO:0030707 follicle cell of egg chamber development; GO:0030713 follicle cell of egg chamber stalk formation; GO:0030718 germ-line stem cell population maintenance; GO:0030720 oocyte localization involved in germarium-derived egg chamber formation; GO:0030900 forebrain development; GO:0031016 pancreas development; GO:0031017 exocrine pancreas development; GO:0031018 endocrine pancreas development; GO:0031069 hair follicle morphogenesis; GO:0031100 animal organ regeneration; GO:0031101 fin regeneration; GO:0031297 replication fork processing; GO:0031441 negative regulation of mRNA 3'-end processing; GO:0032148 activation of protein kinase B activity; GO:0032232 negative regulation of actin filament bundle assembly; GO:0032466 negative regulation of cytokinesis; GO:0032495 response to muramyl dipeptide; GO:0032496 response to lipopolysaccharide; GO:0032966 negative regulation of collagen biosynthetic process; GO:0033601 positive regulation of mammary gland epithelial cell proliferation; GO:0034599 cellular response to oxidative stress; GO:0034614 cellular response to reactive oxygen species; GO:0035019 somatic stem cell population maintenance; GO:0035116 embryonic hindlimb morphogenesis; GO:0035148 tube formation; GO:0035153 epithelial cell type specification, open tracheal system; GO:0035162 embryonic hemopoiesis; GO:0035167 larval lymph gland hemopoiesis; GO:0035171 lamellocyte differentiation; GO:0035172 hemocyte proliferation; GO:0035176 social behavior; GO:0035204 negative regulation of lamellocyte differentiation; GO:0035214 eye-antennal disc development; GO:0035222 wing disc pattern formation; GO:0035264 multicellular organism growth; GO:0035331 negative regulation of hippo signaling; GO:0035418 protein localization to synapse; GO:0035556 intracellular signal transduction; GO:0035622 intrahepatic bile duct development; GO:0035633 maintenance of blood-brain barrier; GO:0035640 exploration behavior; GO:0035641 locomotory exploration behavior; GO:0035825 homologous recombination; GO:0035907 dorsal aorta development; GO:0035914 skeletal muscle cell differentiation; GO:0035924 cellular response to vascular endothelial growth factor stimulus; GO:0036011 imaginal disc-derived leg segmentation; GO:0036099 female germ-line stem cell population maintenance; GO:0036120 cellular response to platelet-derived growth factor stimulus; GO:0036269 swimming behavior; GO:0036335 intestinal stem cell homeostasis; GO:0040008 regulation of growth; GO:0040011 locomotion; GO:0042048 olfactory behavior; GO:0042060 wound healing; GO:0042127 regulation of cell population proliferation; GO:0042177 negative regulation of protein catabolic process; GO:0042246 tissue regeneration; GO:0042297 vocal learning; GO:0042325 regulation of phosphorylation; GO:0042472 inner ear morphogenesis; GO:0042593 glucose homeostasis; GO:0042663 regulation of endodermal cell fate specification; GO:0042686 regulation of cardioblast cell fate specification; GO:0042688 crystal cell differentiation; GO:0042691 positive regulation of crystal cell differentiation; GO:0042742 defense response to bacterium; GO:0043011 myeloid dendritic cell differentiation; GO:0043063 intercellular bridge organization; GO:0043065 positive regulation of apoptotic process; GO:0043066 negative regulation of apoptotic process; GO:0043069 negative regulation of programmed cell death; GO:0043086 negative regulation of catalytic activity; GO:0043114 regulation of vascular permeability; GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043277 apoptotic cell clearance; GO:0043524 negative regulation of neuron apoptotic process; GO:0043525 positive regulation of neuron apoptotic process; GO:0043697 cell dedifferentiation; GO:0044818 mitotic G2/M transition checkpoint; GO:0045070 positive regulation of viral genome replication; GO:0045165 cell fate commitment; GO:0045199 maintenance of epithelial cell apical/basal polarity; GO:0045316 negative regulation of compound eye photoreceptor development; GO:0045466 R7 cell differentiation; GO:0045494 photoreceptor cell maintenance; GO:0045595 regulation of cell differentiation; GO:0045596 negative regulation of cell differentiation; GO:0045603 positive regulation of endothelial cell differentiation; GO:0045607 regulation of inner ear auditory receptor cell differentiation; GO:0045608 negative regulation of inner ear auditory receptor cell differentiation; GO:0045618 positive regulation of keratinocyte differentiation; GO:0045662 negative regulation of myoblast differentiation; GO:0045665 negative regulation of neuron differentiation; GO:0045668 negative regulation of osteoblast differentiation; GO:0045672 positive regulation of osteoclast differentiation; GO:0045687 positive regulation of glial cell differentiation; GO:0045732 positive regulation of protein catabolic process; GO:0045747 positive regulation of Notch signaling pathway; GO:0045786 negative regulation of cell cycle; GO:0045787 positive regulation of cell cycle; GO:0045794 negative regulation of cell volume; GO:0045860 positive regulation of protein kinase activity; GO:0045892 negative regulation of DNA-templated transcription; GO:0045893 positive regulation of DNA-templated transcription; GO:0045944 positive regulation of transcription by RNA polymerase II; GO:0045955 negative regulation of calcium ion-dependent exocytosis; GO:0046331 lateral inhibition; GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT; GO:0046488 phosphatidylinositol metabolic process; GO:0046533 negative regulation of photoreceptor cell differentiation; GO:0046579 positive regulation of Ras protein signal transduction; GO:0046666 retinal cell programmed cell death; GO:0046667 compound eye retinal cell programmed cell death; GO:0046716 muscle cell cellular homeostasis; GO:0046826 negative regulation of protein export from nucleus; GO:0046843 dorsal appendage formation; GO:0046849 bone remodeling; GO:0046959 habituation; GO:0048013 ephrin receptor signaling pathway; GO:0048052 R1/R6 cell differentiation; GO:0048056 R3/R4 cell differentiation; GO:0048103 somatic stem cell division; GO:0048167 regulation of synaptic plasticity; GO:0048170 positive regulation of long-term neuronal synaptic plasticity; GO:0048190 wing disc dorsal/ventral pattern formation; GO:0048259 regulation of receptor-mediated endocytosis; GO:0048337 positive regulation of mesodermal cell fate specification; GO:0048477 oogenesis; GO:0048514 blood vessel morphogenesis; GO:0048542 lymph gland development; GO:0048627 myoblast development; GO:0048661 positive regulation of smooth muscle cell proliferation; GO:0048663 neuron fate commitment; GO:0048664 neuron fate determination; GO:0048665 neuron fate specification; GO:0048699 generation of neurons; GO:0048708 astrocyte differentiation; GO:0048709 oligodendrocyte differentiation; GO:0048711 positive regulation of astrocyte differentiation; GO:0048715 negative regulation of oligodendrocyte differentiation; GO:0048749 compound eye development; GO:0048754 branching morphogenesis of an epithelial tube; GO:0048793 pronephros development; GO:0048803 imaginal disc-derived male genitalia morphogenesis; GO:0048844 artery morphogenesis; GO:0048845 venous blood vessel morphogenesis; GO:0048854 brain morphogenesis; GO:0048863 stem cell differentiation; GO:0048873 homeostasis of number of cells within a tissue; GO:0048936 peripheral nervous system neuron axonogenesis; GO:0050434 positive regulation of viral transcription; GO:0050678 regulation of epithelial cell proliferation; GO:0050679 positive regulation of epithelial cell proliferation; GO:0050767 regulation of neurogenesis; GO:0050768 negative regulation of neurogenesis; GO:0050804 modulation of chemical synaptic transmission; GO:0050808 synapse organization; GO:0050877 nervous system process; GO:0050885 neuromuscular process controlling balance; GO:0050894 determination of affect; GO:0050953 sensory perception of light stimulus; GO:0050957 equilibrioception; GO:0050975 sensory perception of touch; GO:0051124 synaptic assembly at neuromuscular junction; GO:0051152 positive regulation of smooth muscle cell differentiation; GO:0051306 mitotic sister chromatid separation; GO:0051489 regulation of filopodium assembly; GO:0051726 regulation of cell cycle; GO:0051835 positive regulation of synapse structural plasticity; GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; GO:0051968 positive regulation of synaptic transmission, glutamatergic; GO:0055008 cardiac muscle tissue morphogenesis; GO:0055016 hypochord development; GO:0055059 asymmetric neuroblast division; GO:0060013 righting reflex; GO:0060038 cardiac muscle cell proliferation; GO:0060045 positive regulation of cardiac muscle cell proliferation; GO:0060074 synapse maturation; GO:0060113 inner ear receptor cell differentiation; GO:0060122 inner ear receptor cell stereocilium organization; GO:0060218 hematopoietic stem cell differentiation; GO:0060250 germ-line stem-cell niche homeostasis; GO:0060253 negative regulation of glial cell proliferation; GO:0060271 cilium assembly; GO:0060288 formation of a compartment boundary; GO:0060289 compartment boundary maintenance; GO:0060291 long-term synaptic potentiation; GO:0060292 long-term synaptic depression; GO:0060317 cardiac epithelial to mesenchymal transition; GO:0060325 face morphogenesis; GO:0060351 cartilage development involved in endochondral bone morphogenesis; GO:0060354 negative regulation of cell adhesion molecule production; GO:0060379 cardiac muscle cell myoblast differentiation; GO:0060411 cardiac septum morphogenesis; GO:0060412 ventricular septum morphogenesis; GO:0060413 atrial septum morphogenesis; GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; GO:0060571 morphogenesis of an epithelial fold; GO:0060582 cell fate determination involved in pattern specification; GO:0060674 placenta blood vessel development; GO:0060740 prostate gland epithelium morphogenesis; GO:0060749 mammary gland alveolus development; GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development; GO:0060840 artery development; GO:0060842 arterial endothelial cell differentiation; GO:0060843 venous endothelial cell differentiation; GO:0060948 cardiac vascular smooth muscle cell development; GO:0060956 endocardial cell differentiation; GO:0060979 vasculogenesis involved in coronary vascular morphogenesis; GO:0060982 coronary artery morphogenesis; GO:0060997 dendritic spine morphogenesis; GO:0060999 positive regulation of dendritic spine development; GO:0061001 regulation of dendritic spine morphogenesis; GO:0061056 sclerotome development; GO:0061073 ciliary body morphogenesis; GO:0061314 Notch signaling involved in heart development; GO:0061331 epithelial cell proliferation involved in Malpighian tubule morphogenesis; GO:0061344 regulation of cell adhesion involved in heart morphogenesis; GO:0061351 neural precursor cell proliferation; GO:0061382 Malpighian tubule tip cell differentiation; GO:0061384 heart trabecula morphogenesis; GO:0062043 positive regulation of cardiac epithelial to mesenchymal transition; GO:0065003 protein-containing complex assembly; GO:0070168 negative regulation of biomineral tissue development; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0070986 left/right axis specification; GO:0071168 protein localization to chromatin; GO:0071228 cellular response to tumor cell; GO:0071372 cellular response to follicle-stimulating hormone stimulus; GO:0071394 cellular response to testosterone stimulus; GO:0071456 cellular response to hypoxia; GO:0071479 cellular response to ionizing radiation; GO:0071625 vocalization behavior; GO:0072014 proximal tubule development; GO:0072015 podocyte development; GO:0072017 distal tubule development; GO:0072044 collecting duct development; GO:0072104 glomerular capillary formation; GO:0072144 glomerular mesangial cell development; GO:0072538 T-helper 17 type immune response; GO:0072574 hepatocyte proliferation; GO:0072576 liver morphogenesis; GO:0085020 protein K6-linked ubiquitination; GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis; GO:0090090 negative regulation of canonical Wnt signaling pathway; GO:0097107 postsynaptic density assembly; GO:0097113 AMPA glutamate receptor clustering; GO:0097114 NMDA glutamate receptor clustering; GO:0097117 guanylate kinase-associated protein clustering; GO:0097120 receptor localization to synapse; GO:0097150 neuronal stem cell population maintenance; GO:0097396 response to interleukin-17; GO:0097400 interleukin-17-mediated signaling pathway; GO:0097746 blood vessel diameter maintenance; GO:0098725 symmetric cell division; GO:0098990 AMPA selective glutamate receptor signaling pathway; GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels; GO:0099151 regulation of postsynaptic density assembly; GO:0099159 regulation of modification of postsynaptic structure; GO:0099175 regulation of postsynapse organization; GO:0099527 postsynapse to nucleus signaling pathway; GO:0099565 chemical synaptic transmission, postsynaptic; GO:0110025 DNA strand resection involved in replication fork processing; GO:0120011 intermembrane sterol transfer; GO:0120054 intestinal motility; GO:0120163 negative regulation of cold-induced thermogenesis; GO:1900087 positive regulation of G1/S transition of mitotic cell cycle; GO:1900271 regulation of long-term synaptic potentiation; GO:1900273 positive regulation of long-term synaptic potentiation; GO:1900383 regulation of synaptic plasticity by receptor localization to synapse; GO:1900451 positive regulation of glutamate receptor signaling pathway; GO:1900452 regulation of long-term synaptic depression; GO:1901189 positive regulation of ephrin receptor signaling pathway; GO:1901201 regulation of extracellular matrix assembly; GO:1901222 regulation of non-canonical NF-kappaB signal transduction; GO:1902263 apoptotic process involved in embryonic digit morphogenesis; GO:1902339 positive regulation of apoptotic process involved in morphogenesis; GO:1902692 regulation of neuroblast proliferation; GO:1902895 positive regulation of miRNA transcription; GO:1903849 positive regulation of aorta morphogenesis; GO:1904044 response to aldosterone; GO:1904717 regulation of AMPA glutamate receptor clustering; GO:1905275 Rohon-Beard neuron differentiation; GO:1905430 cellular response to glycine; GO:1990255 subsynaptic reticulum organization; GO:1990705 cholangiocyte proliferation; GO:1990798 pancreas regeneration; GO:1990830 cellular response to leukemia inhibitory factor; GO:1990911 response to psychosocial stress; GO:2000001 regulation of DNA damage checkpoint; GO:2000010 positive regulation of protein localization to cell surface; GO:2000035 regulation of stem cell division; GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin; GO:2000050 regulation of non-canonical Wnt signaling pathway; GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis; GO:2000369 regulation of clathrin-dependent endocytosis; GO:2000463 positive regulation of excitatory postsynaptic potential; GO:2000737 negative regulation of stem cell differentiation; GO:2000811 negative regulation of anoikis; GO:2000821 regulation of grooming behavior; GO:2000822 regulation of behavioral fear response; GO:2000974 negative regulation of pro-B cell differentiation; GO:2001027 negative regulation of endothelial cell chemotaxis; GO:2001204 regulation of osteoclast development; GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

KEGG

EC: ec:2.7.10.2 | KO: K02599, K05293, K06867, K09257, K10683, K12491, K15009, K17266, K17512, K17540, K17554, K17566, K17848, K19626, K20129, K20456, K20994, K20995, K20996, K21411, K21413, K21414, K21415, K21436, K21437, K21441, K21596, K21878, K21952, K25576 | Pathway: 00563, 01100, 01522, 03440, 04013, 04068, 04144, 04320, 04330, 04361, 04371, 04658, 04724, 04919, 05020, 05165, 05200, 05206, 05207, 05224 | BRITE: 00001, 01000, 01001, 01009, 03000, 03019, 03036, 03037, 03400, 04121, 04131, 04147