Chr12.g78513

Functional evidence

eggNOG

4432.XP_010255402.1,C,[lysine-specific demethylase]

Gene Ontology

lysine-specific demethylase | GO:0000122//negative regulation of transcription from RNA polymerase II promoter; GO:0006325//chromatin organization; GO:0006355//regulation of transcription, DNA-templated; GO:0006357//regulation of transcription from RNA polymerase II promoter; GO:0006464//cellular protein modification process; GO:0006482//protein demethylation; GO:0006807//nitrogen compound metabolic process; GO:0006996//organelle organization; GO:0007623//circadian rhythm; GO:0008150//biological_process; GO:0008152//metabolic process; GO:0008214//protein dealkylation; GO:0009889//regulation of biosynthetic process; GO:0009890//negative regulation of biosynthetic process; GO:0009891//positive regulation of biosynthetic process; GO:0009892//negative regulation of metabolic process; GO:0009893//positive regulation of metabolic process; GO:0009987//cellular process; GO:0010468//regulation of gene expression; GO:0010556//regulation of macromolecule biosynthetic process; GO:0010557//positive regulation of macromolecule biosynthetic process; GO:0010558//negative regulation of macromolecule biosynthetic process; GO:0010604//positive regulation of macromolecule metabolic process; GO:0010605//negative regulation of macromolecule metabolic process; GO:0010628//positive regulation of gene expression; GO:0010629//negative regulation of gene expression; GO:0010639//negative regulation of organelle organization; GO:0016043//cellular component organization; GO:0016569//covalent chromatin modification; GO:0016570//histone modification; GO:0016577//histone demethylation; GO:0019219//regulation of nucleobase-containing compound metabolic process; GO:0019222//regulation of metabolic process; GO:0019538//protein metabolic process; GO:0031056//regulation of histone modification; GO:0031057//negative regulation of histone modification; GO:0031063//regulation of histone deacetylation; GO:0031064//negative regulation of histone deacetylation; GO:0031323//regulation of cellular metabolic process; GO:0031324//negative regulation of cellular metabolic process; GO:0031325//positive regulation of cellular metabolic process; GO:0031326//regulation of cellular biosynthetic process; GO:0031327//negative regulation of cellular biosynthetic process; GO:0031328//positive regulation of cellular biosynthetic process; GO:0031399//regulation of protein modification process; GO:0031400//negative regulation of protein modification process; GO:0032268//regulation of cellular protein metabolic process; GO:0032269//negative regulation of cellular protein metabolic process; GO:0032501//multicellular organismal process; GO:0032922//circadian regulation of gene expression; GO:0033043//regulation of organelle organization; GO:0033044//regulation of chromosome organization; GO:0034720//histone H3-K4 demethylation; GO:0034721//histone H3-K4 demethylation, trimethyl-H3-K4-specific; GO:0036211//protein modification process; GO:0043086//negative regulation of catalytic activity; GO:0043170//macromolecule metabolic process; GO:0043412//macromolecule modification; GO:0044092//negative regulation of molecular function; GO:0044237//cellular metabolic process; GO:0044238//primary metabolic process; GO:0044260//cellular macromolecule metabolic process; GO:0044267//cellular protein metabolic process; GO:0045892//negative regulation of transcription, DNA-templated; GO:0045893//positive regulation of transcription, DNA-templated; GO:0045934//negative regulation of nucleobase-containing compound metabolic process; GO:0045935//positive regulation of nucleobase-containing compound metabolic process; GO:0048511//rhythmic process; GO:0048518//positive regulation of biological process; GO:0048519//negative regulation of biological process; GO:0048522//positive regulation of cellular process; GO:0048523//negative regulation of cellular process; GO:0050789//regulation of biological process; GO:0050790//regulation of catalytic activity; GO:0050794//regulation of cellular process; GO:0051090//regulation of sequence-specific DNA binding transcription factor activity; GO:0051128//regulation of cellular component organization; GO:0051129//negative regulation of cellular component organization; GO:0051171//regulation of nitrogen compound metabolic process; GO:0051172//negative regulation of nitrogen compound metabolic process; GO:0051173//positive regulation of nitrogen compound metabolic process; GO:0051246//regulation of protein metabolic process; GO:0051248//negative regulation of protein metabolic process; GO:0051252//regulation of RNA metabolic process; GO:0051253//negative regulation of RNA metabolic process; GO:0051254//positive regulation of RNA metabolic process; GO:0051276//chromosome organization; GO:0051336//regulation of hydrolase activity; GO:0051346//negative regulation of hydrolase activity; GO:0060255//regulation of macromolecule metabolic process; GO:0065007//biological regulation; GO:0065009//regulation of molecular function; GO:0070076//histone lysine demethylation; GO:0070988//demethylation; GO:0071704//organic substance metabolic process; GO:0071840//cellular component organization or biogenesis; GO:0080090//regulation of primary metabolic process; GO:0090311//regulation of protein deacetylation; GO:1901564//organonitrogen compound metabolic process; GO:1901725//regulation of histone deacetylase activity; GO:1901726//negative regulation of histone deacetylase activity; GO:1902275//regulation of chromatin organization; GO:1902679//negative regulation of RNA biosynthetic process; GO:1902680//positive regulation of RNA biosynthetic process; GO:1903506//regulation of nucleic acid-templated transcription; GO:1903507//negative regulation of nucleic acid-templated transcription; GO:1903508//positive regulation of nucleic acid-templated transcription; GO:1905268//negative regulation of chromatin organization; GO:2000112//regulation of cellular macromolecule biosynthetic process; GO:2000113//negative regulation of cellular macromolecule biosynthetic process; GO:2001141//regulation of RNA biosynthetic process; GO:2001251//negative regulation of chromosome organization | GO:0005575//cellular_component; GO:0005622//intracellular; GO:0005623//cell; GO:0005634//nucleus; GO:0032991//macromolecular complex; GO:0032993//protein-DNA complex; GO:0043226//organelle; GO:0043227//membrane-bounded organelle; GO:0043229//intracellular organelle; GO:0043231//intracellular membrane-bounded organelle; GO:0044424//intracellular part; GO:0044464//cell part | GO:0000976//transcription regulatory region sequence-specific DNA binding; GO:0001046//core promoter sequence-specific DNA binding; GO:0001047//core promoter binding; GO:0001067//regulatory region nucleic acid binding; GO:0003674//molecular_function; GO:0003676//nucleic acid binding; GO:0003677//DNA binding; GO:0003682//chromatin binding; GO:0003690//double-stranded DNA binding; GO:0003700//transcription factor activity, sequence-specific DNA binding; GO:0003712//transcription cofactor activity; GO:0003713//transcription coactivator activity; GO:0003824//catalytic activity; GO:0005488//binding; GO:0005515//protein binding; GO:0008270//zinc ion binding; GO:0031490//chromatin DNA binding; GO:0032451//demethylase activity; GO:0032452//histone demethylase activity; GO:0032453//histone demethylase activity (H3-K4 specific); GO:0034647//histone demethylase activity (H3-trimethyl-K4 specific); GO:0034648//histone demethylase activity (H3-dimethyl-K4 specific); GO:0035064//methylated histone binding; GO:0042393//histone binding; GO:0043167//ion binding; GO:0043169//cation binding; GO:0043565//sequence-specific DNA binding; GO:0044212//transcription regulatory region DNA binding; GO:0046872//metal ion binding; GO:0046914//transition metal ion binding; GO:0097159//organic cyclic compound binding; GO:1901363//heterocyclic compound binding; GO:1990837//sequence-specific double-stranded DNA binding

KEGG

K11446 | KDM5, JARID1

NR

XP_010255404.1 PREDICTED: lysine-specific demethylase 5B isoform X2 [Nelumbo nucifera]

Swiss-Prot

Q30DN6.1 RecName: Full=Lysine-specific demethylase 5D; AltName: Full=Histone demethylase JARID1D; AltName: Full=Jumonji/ARID domain-containing protein 1D; AltName: Full=Protein SmcY; AltName: Full=[histone H3]-trimethyl-L-lysine(4) demethylase 5D [Canis lupus familiaris]