Functional discovery

Search genes by biological annotation

Search integrated eggNOG, Gene Ontology, and KEGG evidence with phrases such as fatty acid, lipid metabolism, kinase, or transcription factor.

33,382
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3+
indexed evidence types

Keyword matching is case-insensitive. Results remain collection-specific and represent computational annotation evidence, not experimental validation.

Matches

2,418 genes for “transcription factor”

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GO enrichmentExport FASTA
SelectGeneMatched annotationEvidenceActions
PaHa_c387g00130PaHa_c387g00130.1

… GO:0016251 | GO:0045944 | chromatin | chromatin binding | cellular_component | nucleus | transcription factor TFIID complex | cytosol | transcription by RNA polymerase II | transcription initiation at RNA polymerase II promoter | biological_process | RNA polymerase II general transcription initiati…

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eggNOG
Preferred name: TAF3 | Seed ortholog: 1287680.R1GMG6 | COG: S | eggNOG OG: Bromo_TP@131567|A-1*, Bromo_TP@2759|Ad-7
GO
GO:0000785 chromatin; GO:0003682 chromatin binding; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0005669 transcription factor TFIID complex; GO:0005829 cytosol; GO:0006366 transcription by RNA polymerase II; GO:0006367 transcription initiation at RNA polymerase II promoter; GO:0008150 biological_process; GO:0016251 RNA polymerase II general transcription initiation factor activity; GO:0045944 positive...
KEGG
KO: K14650 | Pathway: 03022 | BRITE: 00001, 03021
eggNOGGOKEGG
eggNOG-inferred
PaHa_c396g00080PaHa_c396g00080.1

…66 | GO:0006367 | GO:0008270 | GO:0016251 | nucleotide-excision repair factor 3 complex | transcription factor TFIIH core complex | molecular_function | cellular_component | nucleus | transcription factor TFIIH holo complex | cytosol | nucleotide-excision repair | transcription by RNA polymerase II …

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eggNOG
Preferred name: TFB4 | Seed ortholog: 1157616.A0A1Z5SYC7 | COG: S | eggNOG OG: Tfb4@2759|A-1
GO
GO:0000112 nucleotide-excision repair factor 3 complex; GO:0000439 transcription factor TFIIH core complex; GO:0003674 molecular_function; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0005675 transcription factor TFIIH holo complex; GO:0005829 cytosol; GO:0006289 nucleotide-excision repair; GO:0006366 transcription by RNA polymerase II; GO:0006367 transcription initiation at RNA polymerase II promoter; GO...
KEGG
EC: ec:2.1.1.57 | KO: K03143 | Pathway: 03022, 03420 | BRITE: 00001, 03021, 03400
eggNOGGOKEGG
eggNOG-inferred
PaHa_c410g00200PaHa_c410g00200.1

PaHa_c410g00200 | PaHa_c410g00200.1 | rlcA | 1016849.A0A0D1YCJ3 | PHD@131567|A-1* | PHD@2759|Dw-9 | SPOC@131567|A-1* | SPOC@2759|N-4! | TFIIS_M@131567|A-1* | TFIIS_M@2759|B-2 | S | ec:6.1.1.6 | K04567 | 00970 | 00001 | 01000 | 01007 | 01613 | 03016 | PHD_55...

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eggNOG
Preferred name: rlcA | Seed ortholog: 1016849.A0A0D1YCJ3 | COG: S | eggNOG OG: PHD@131567|A-1*, PHD@2759|Dw-9, SPOC@131567|A-1*, SPOC@2759|N-4!, TFIIS_M@131567|A-1*, TFIIS_M@2759|B-2
GO
GO:0000122 negative regulation of transcription by RNA polymerase II; GO:0003674 molecular_function; GO:0003682 chromatin binding; GO:0003711 transcription elongation factor activity; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0008270 zinc ion binding; GO:0034244 negative regulation of transcription elongation by RNA polymerase II; GO:0140002 histone H3K4me3 reader activity
KEGG
EC: ec:6.1.1.6 | KO: K04567 | Pathway: 00970 | BRITE: 00001, 01000, 01007, 01613, 03016
eggNOGGOKEGG
eggNOG-inferred
PaHa_c410g00210PaHa_c410g00210.1

PaHa_c410g00210 | PaHa_c410g00210.1 | BYE1 | 1168221.R7Z2N7 | PHD@131567|A-1* | PHD@2759|Dw-9 | SPOC@131567|A-1* | SPOC@2759|N-4! | TFIIS_M@131567|A-1* | TFIIS_M@2759|B-2 | S | ec:6.1.1.6 | K04567 | 00970 | 00001 | 01000 | 01007 | 01613 | 03016 | PHD_54_104...

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eggNOG
Preferred name: BYE1 | Seed ortholog: 1168221.R7Z2N7 | COG: S | eggNOG OG: PHD@131567|A-1*, PHD@2759|Dw-9, SPOC@131567|A-1*, SPOC@2759|N-4!, TFIIS_M@131567|A-1*, TFIIS_M@2759|B-2
GO
GO:0000122 negative regulation of transcription by RNA polymerase II; GO:0003674 molecular_function; GO:0003682 chromatin binding; GO:0003711 transcription elongation factor activity; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0008270 zinc ion binding; GO:0034244 negative regulation of transcription elongation by RNA polymerase II; GO:0140002 histone H3K4me3 reader activity
KEGG
EC: ec:6.1.1.6 | KO: K04567 | Pathway: 00970 | BRITE: 00001, 01000, 01007, 01613, 03016
eggNOGGOKEGG
eggNOG-inferred
PaHa_c413g00110PaHa_c413g00110.1

…regulation of transcription by RNA polymerase II | RNA polymerase II-specific DNA-binding transcription factor binding | cellular response to xenobiotic stimulus | positive regulation of filamentous growth of a population of unicellular organisms | positive regulation of filamentous growth of a popu…

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eggNOG
Preferred name: ARID2401 | Seed ortholog: 112498.A0A2D3URT2 | COG: S | eggNOG OG: ARID@131567|A-1*, ARID@2759|CG-9, ARID@33154|Ll-14
GO
GO:0000785 chromatin; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0006261 DNA-templated DNA replication; GO:0006338 chromatin remodeling; GO:0006355 regulation of DNA-templated transcription; GO:0006357 regulation of transcription by RNA polymerase II; GO:0007155 cell adhesion; GO:0008270 zinc ion binding; GO:0016514 SWI/SNF complex; GO:0030447 filamentous growth; GO:0031496 positive regulation of mating...
KEGG
KO: K11771 | Pathway: 03083, 04550 | BRITE: 00001, 03021, 03036
eggNOGGOKEGG
eggNOG-inferred
PaHa_c422g00170PaHa_c422g00170.1

PaHa_c422g00170 | PaHa_c422g00170.1 | TAF10 | 1328760.A0A164ZTA5 | TFIID_30kDa@2759|A-1 | S | K03134 | K22485 | 03022 | 00001 | 03021 | 03032 | 03036 | TFIID_30kDa_122_174 | GO:0000082 | GO:0000124 | GO:0001701 | GO:0001756 | GO:0001889 | GO:0001892 | GO...

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eggNOG
Preferred name: TAF10 | Seed ortholog: 1328760.A0A164ZTA5 | COG: S | eggNOG OG: TFIID_30kDa@2759|A-1
GO
GO:0000082 G1/S transition of mitotic cell cycle; GO:0000124 SAGA complex; GO:0001701 in utero embryonic development; GO:0001756 somitogenesis; GO:0001889 liver development; GO:0001892 embryonic placenta development; GO:0003674 molecular_function; GO:0003677 DNA binding; GO:0003682 chromatin binding; GO:0003713 transcription coactivator activity; GO:0004402 histone acetyltransferase activity; GO:0005515 protein...
KEGG
KO: K03134, K22485 | Pathway: 03022 | BRITE: 00001, 03021, 03032, 03036
eggNOGGOKEGG
eggNOG-inferred
PaHa_c428g00020PaHa_c428g00020.1

PaHa_c428g00020 | PaHa_c428g00020.1 | MMS2 | 1507870.A0A1V8T105 | UQ_con@131567|DJ-11 | UQ_con@2759|EN-12 | UQ_con@470018|QKB-46 | S | ec:1.14.19.77 | K10704 | K26392 | 00565 | 01100 | 04624 | 05131 | 00001 | 02000 | 03400 | UQ_con_37_131 | GO:0000151 | GO...

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eggNOG
Preferred name: MMS2 | Seed ortholog: 1507870.A0A1V8T105 | COG: S | eggNOG OG: UQ_con@131567|DJ-11, UQ_con@2759|EN-12, UQ_con@470018|QKB-46
GO
GO:0000151 ubiquitin ligase complex; GO:0000209 protein polyubiquitination; GO:0000329 fungal-type vacuole membrane; GO:0000729 DNA double-strand break processing; GO:0004842 ubiquitin-protein transferase activity; GO:0005515 protein binding; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0005737 cytoplasm; GO:0005739 mitochondrion; GO:0005783 endoplasmic reticulum; GO:0005829...
KEGG
EC: ec:1.14.19.77 | KO: K10704, K26392 | Pathway: 00565, 01100, 04624, 05131 | BRITE: 00001, 02000, 03400
eggNOGGOKEGG
eggNOG-inferred
PaHa_c436g00160PaHa_c436g00160.1

PaHa_c436g00160 | PaHa_c436g00160.1 | AGO5 | 71139.A0A059DA63 | ArgoL1@131221|jP-19 | ArgoL1@131567|A-1* | ArgoL1@2759|C-2! | ArgoL1@35493|MZ-14 | ArgoL2@131221|Ii-13 | ArgoL2@131567|A-1* | ArgoL2@1437183|iM-19 | ArgoL2@2759|C-2 | ArgoL2@3193|LN-14 | ArgoL2...

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eggNOG
Preferred name: AGO5 | Seed ortholog: 71139.A0A059DA63 | COG: S | eggNOG OG: ArgoL1@131221|jP-19, ArgoL1@131567|A-1*, ArgoL1@2759|C-2!, ArgoL1@35493|MZ-14, ArgoL2@131221|Ii-13, ArgoL2@131567|A-1*, ArgoL2@1437183|iM-19, ArgoL2@2759|C-2, ArgoL2@3193|LN-14, ArgoL2@35493|Cr-10, ArgoMid@131567|A-1*, ArgoMid@2759|An-8, ArgoMid@3193|Mc-15, ArgoN@131221|RT-15, ArgoN@131567|A-1*, ArgoN@2759|C-2!, ArgoN@3193|Ws-16, ArgoN...
GO
GO:0000340 RNA 7-methylguanosine cap binding; GO:0000976 transcription cis-regulatory region binding; GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding; GO:0000993 RNA polymerase II complex binding; GO:0001046 core promoter sequence-specific DNA binding; GO:0003676 nucleic acid binding; GO:0003723 RNA binding; GO:0003725 double-stranded RNA binding; GO:0003727 single-stranded RNA...
KEGG
KO: K11593 | Pathway: 04320, 04361 | BRITE: 00001, 03019, 03036
eggNOGGOKEGG
eggNOG-inferred
PaHa_c78g00100PaHa_c78g00100.1

PaHa_c78g00100 | PaHa_c78g00100.1 | YSH1 | 1328760.A0A165HV81 | Beta-Casp@131567|K-4 | Beta-Casp@2759|AH-8 | CPSF73-100_C@2759|A-1 | Lactamase_B@131567|Cp-10 | RMMBL@131567|B-2 | RMMBL@2759|Ch-11 | COG1236 | K14403 | 03015 | 00001 | 03019 | 03021 | Beta...

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eggNOG
Preferred name: YSH1 | Seed ortholog: 1328760.A0A165HV81 | COG: COG1236 | eggNOG OG: Beta-Casp@131567|K-4, Beta-Casp@2759|AH-8, CPSF73-100_C@2759|A-1, Lactamase_B@131567|Cp-10, RMMBL@131567|B-2, RMMBL@2759|Ch-11
GO
GO:0003674 molecular_function; GO:0004521 RNA endonuclease activity; GO:0005515 protein binding; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0005829 cytosol; GO:0005847 mRNA cleavage and polyadenylation specificity factor complex; GO:0006369 termination of RNA polymerase II transcription; GO:0006397 mRNA processing; GO:0008150 biological_process; GO:0008270 zinc ion binding; GO:0008380 RNA splicing; GO...
KEGG
KO: K14403 | Pathway: 03015 | BRITE: 00001, 03019, 03021
eggNOGGOKEGG
eggNOG-inferred
PaHa_c81g00010PaHa_c81g00010.1

…O:0003677 | GO:0003700 | GO:0005515 | GO:0005634 | GO:0009408 | DNA binding | DNA-binding transcription factor activity | protein binding | nucleus | response to heat

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eggNOG
Preferred name: HSFA1 | Seed ortholog: 337451.A0A3S3MV96 | COG: S | eggNOG OG: HSF_DNA-bind@131567|Dp-10, HSF_DNA-bind@3193|AWd-23, HSF_DNA-bind@33090|fZ-18, HSF_DNA-bind@3398|BEb-26, HSF_DNA-bind@35493|uY-20
GO
GO:0003677 DNA binding; GO:0003700 DNA-binding transcription factor activity; GO:0005515 protein binding; GO:0005634 nucleus; GO:0009408 response to heat
KEGG
KO: K09419 | BRITE: 00001, 03000
eggNOGGOKEGG
eggNOG-inferred
PaHa_c81g00040PaHa_c81g00040.1

…48439 | GO:0048571 | GO:0048577 | GO:0048579 | GO:0071558 | heterochromatin | DNA-binding transcription factor activity | nucleus | regulation of DNA-templated transcription | response to temperature stimulus | histone demethylase activity | histone H3K9 demethylase activity | histone binding | nega…

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eggNOG
Preferred name: REF6 | Seed ortholog: 337451.A0A3S3NUI3 | COG: S | eggNOG OG: JmjC@131567|Ae-7, JmjC@2759|IC-12!, JmjC@33090|Xb-17, JmjC@58023|Adw-25, JmjN@131567|A-1*, JmjN@2759|U-5!, JmjN@33090|BQ-10, JmjN@3398|FO-14, zf-C5HC2@131567|A-1*, zf-C5HC2@2759|C-2!, zf-C5HC2@3398|Fx-13
GO
GO:0000792 heterochromatin; GO:0003700 DNA-binding transcription factor activity; GO:0005634 nucleus; GO:0006355 regulation of DNA-templated transcription; GO:0009266 response to temperature stimulus; GO:0032452 histone demethylase activity; GO:0032454 histone H3K9 demethylase activity; GO:0042393 histone binding; GO:0045814 negative regulation of gene expression, epigenetic; GO:0045815 transcription initiation...
KEGG
EC: ec:1.14.11.66, ec:1.14.11.67, ec:1.14.11.69 | KO: K06709, K11446, K11478 | Pathway: 03083, 04550 | BRITE: 00001, 01000, 01009, 03036
eggNOGGOKEGG
eggNOG-inferred
PaHa_c8g00080PaHa_c8g00080.1

…GO:0097718 | GO:0140296 | GO:0140297 | RNA polymerase I transcription regulator complex | transcription factor TFIIIB complex | chromatin | euchromatin | transcription cis-regulatory region binding | RNA polymerase II cis-regulatory region sequence-specific DNA binding | RNA polymerase II core promo…

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eggNOG
Preferred name: LOC101507215 | Seed ortholog: 888268.A0A1E5V4R0 | COG: S | eggNOG OG: TBP@131567|A-1, TBP@1437183|AIg-34, TBP@147369|Adv-39, TBP@2759|Hc-14, TBP@3398|ABc-32
GO
GO:0000120 RNA polymerase I transcription regulator complex; GO:0000126 transcription factor TFIIIB complex; GO:0000785 chromatin; GO:0000791 euchromatin; GO:0000976 transcription cis-regulatory region binding; GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding; GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding; GO:0000995 RNA polymerase III general...
KEGG
KO: K03120 | Pathway: 03022 | BRITE: 00001, 03000, 03021
eggNOGGOKEGG
eggNOG-inferred
PaHa_c94g00460PaHa_c94g00460.1

PaHa_c94g00460 | PaHa_c94g00460.1 | PFS2 | 1043003.A0A074W238 | WD40@131567|Uz-14 | WD40@2759|ANy-18 | S | K15542 | 03015 | 00001 | 03019 | WD40_125_157 | WD40_162_199 | WD40_208_241 | WD40_245_284 | WD40_365_396 | GO:0000785 | GO:0003674 | GO:0003723 | GO...

Show annotation evidence
eggNOG
Preferred name: PFS2 | Seed ortholog: 1043003.A0A074W238 | COG: S | eggNOG OG: WD40@131567|Uz-14, WD40@2759|ANy-18
GO
GO:0000785 chromatin; GO:0003674 molecular_function; GO:0003723 RNA binding; GO:0005634 nucleus; GO:0005829 cytosol; GO:0005847 mRNA cleavage and polyadenylation specificity factor complex; GO:0006397 mRNA processing; GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled; GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway
KEGG
KO: K15542 | Pathway: 03015 | BRITE: 00001, 03019
eggNOGGOKEGG
eggNOG-inferred
PaHa_c99g00030PaHa_c99g00030.1

PaHa_c99g00030 | PaHa_c99g00030.1 | Cstf2 | 1658172.A0A1B7P0I2 | CSTF2_hinge@2759|A-1 | CSTF_C@2759|A-1 | RRM_1@131567|HCP-31 | COG0724 | ec:4.3.1.17 | ec:4.3.1.19 | K14407 | 03015 | M00570 | 00001 | 03019 | CSTF2_hinge_121_201 | CSTF_C_263_303 | RRM_1_10...

Show annotation evidence
eggNOG
Preferred name: Cstf2 | Seed ortholog: 1658172.A0A1B7P0I2 | COG: COG0724 | eggNOG OG: CSTF2_hinge@2759|A-1, CSTF_C@2759|A-1, RRM_1@131567|HCP-31
GO
GO:0003723 RNA binding; GO:0003729 mRNA binding; GO:0005515 protein binding; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0005829 cytosol; GO:0005847 mRNA cleavage and polyadenylation specificity factor complex; GO:0005848 mRNA cleavage stimulating factor complex; GO:0005849 mRNA cleavage factor complex; GO:0006397 mRNA processing; GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled...
KEGG
EC: ec:4.3.1.17, ec:4.3.1.19 | KO: K14407 | Pathway: 03015 | Module: M00570 | BRITE: 00001, 03019
eggNOGGOKEGG
eggNOG-inferred
PaHa_c99g00040PaHa_c99g00040.1

PaHa_c99g00040 | PaHa_c99g00040.1 | Cstf2 | 331657.A0A4U0X5I2 | RRM_1@131567|HCP-31 | COG0724 | K14407 | 03015 | 00001 | 03019 | RRM_1_10_80 | GO:0003723 | GO:0003729 | GO:0005515 | GO:0005575 | GO:0005634 | GO:0005737 | GO:0005829 | GO:0005847 | GO:0005848...

Show annotation evidence
eggNOG
Preferred name: Cstf2 | Seed ortholog: 331657.A0A4U0X5I2 | COG: COG0724 | eggNOG OG: RRM_1@131567|HCP-31
GO
GO:0003723 RNA binding; GO:0003729 mRNA binding; GO:0005515 protein binding; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0005737 cytoplasm; GO:0005829 cytosol; GO:0005847 mRNA cleavage and polyadenylation specificity factor complex; GO:0005848 mRNA cleavage stimulating factor complex; GO:0005849 mRNA cleavage factor complex; GO:0006396 RNA processing; GO:0006397 mRNA processing; GO:0008150 biological...
KEGG
KO: K14407 | Pathway: 03015 | BRITE: 00001, 03019
eggNOGGOKEGG
eggNOG-inferred
PaHa_c99g00160PaHa_c99g00160.1

…on of transcription by RNA polymerase II | molecular_function | DNA binding | DNA-binding transcription factor activity | transcription coactivator activity | transcription corepressor activity | protein binding | cellular_component | nucleus | pericentric heterochromatin | cytosol | double-strand b…

Show annotation evidence
eggNOG
Preferred name: SIN3 | Seed ortholog: 1126212.K2SAY4 | COG: S | eggNOG OG: PAH@131567|A-1*, PAH@2759|s-7, Sin3_corepress@2759|A-1, Sin3a_C@2759|A-1
GO
GO:0000086 G2/M transition of mitotic cell cycle; GO:0000122 negative regulation of transcription by RNA polymerase II; GO:0003674 molecular_function; GO:0003677 DNA binding; GO:0003700 DNA-binding transcription factor activity; GO:0003713 transcription coactivator activity; GO:0003714 transcription corepressor activity; GO:0005515 protein binding; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0005721...
KEGG
KO: K11644 | Pathway: 04139 | BRITE: 00001, 03036
eggNOGGOKEGG
eggNOG-inferred
PaHa_c99g00170PaHa_c99g00170.1

…on of transcription by RNA polymerase II | molecular_function | DNA binding | DNA-binding transcription factor activity | transcription coactivator activity | transcription corepressor activity | protein binding | cellular_component | nucleus | pericentric heterochromatin | cytosol | double-strand b…

Show annotation evidence
eggNOG
Preferred name: SNT2401 | Seed ortholog: 331657.A0A4V5NGZ5 | COG: S | eggNOG OG: PAH@131567|A-1*, PAH@2759|s-7, Sin3_corepress@2759|A-1, Sin3a_C@2759|A-1
GO
GO:0000086 G2/M transition of mitotic cell cycle; GO:0000122 negative regulation of transcription by RNA polymerase II; GO:0003674 molecular_function; GO:0003677 DNA binding; GO:0003700 DNA-binding transcription factor activity; GO:0003713 transcription coactivator activity; GO:0003714 transcription corepressor activity; GO:0005515 protein binding; GO:0005575 cellular_component; GO:0005634 nucleus; GO:0005721...
KEGG
KO: K11644 | Pathway: 04139 | BRITE: 00001, 03036
eggNOGGOKEGG
eggNOG-inferred
PaHa_c99g00390PaHa_c99g00390.1

… binding | DNA-binding transcription repressor activity | chromatin binding | DNA-binding transcription factor activity | protein binding | nucleus | nucleoplasm | chromatin silencing complex | chromosome | mitochondrion | cytosol | chromatin organization | chromatin remodeling | imaginal disc morph…

Show annotation evidence
eggNOG
Preferred name: Pbrm1 | Seed ortholog: 1328760.A0A165JAG2 | COG: S | eggNOG OG: BAH@131567|A-1*, BAH@2759|BM-9
GO
GO:0000785 chromatin; GO:0000976 transcription cis-regulatory region binding; GO:0001217 DNA-binding transcription repressor activity; GO:0003682 chromatin binding; GO:0003700 DNA-binding transcription factor activity; GO:0005515 protein binding; GO:0005634 nucleus; GO:0005654 nucleoplasm; GO:0005677 chromatin silencing complex; GO:0005694 chromosome; GO:0005739 mitochondrion; GO:0005829 cytosol; GO:0006325...
KEGG
EC: ec:2.7.7.7 | KO: K02350 | BRITE: 00001, 01000, 01612, 03400
eggNOGGOKEGG
eggNOG-inferred

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